Our Research

CLAP Study

 

Now recruiting participants diagnosed with Bipolar Disorder.

Prinicipal Investigator: Anna Manelis, PhD
Co-Investigators: Mary Phillips, MD, Holly Swartz, MD

 

PUBLIC HEALTH RELEVANCE: The ability to prepare for emotional and cognitive tasks is critical to our daily life. The fact that individuals with unipolar depression and bipolar disorder are impaired on performance of emotional and cognitive tasks may be related to their inability to prepare for these tasks. This project aims to compare brain mechanisms of task anticipation in depressed individuals with unipolar and bipolar disorder, thereby targeting identification of potential brain biomarkers for these disorders, and facilitating the development of appropriately targeted treatment strategies.

 

Participation in the CLAP Study may involve: The study may involve five (5) visits over 1-year period. The study participation starts with a lifetime psychiatric evaluation (Visit 1) and, if eligible, the Functional Magnetic Resonance Imaging (or fMRI) scan (Visit 2). fMRI technique is based on radio waves and magnetic fields and it is NOT painful or harmful and DOES NOT involve needles or blood. In 6 months after that, participants may be invited for follow-up clinical (Visit 3) and fMRI (Visit 4) appointments. In 6 more months, participants may be invited for the last clinical appointment (Visit 5). Participation in the study will involve completing questionnaires and various computer tasks. Compensation will be provided for each study visit.

 

Participants must be:

  • Between the ages of 18 and 45
  • Native English speaker
  • Have a history of depression/mania OR have NO history of any psychiatric disorders
  • Not currently in a manic state

For more information:

Email: clap@upmc.edu (preferred)

Call: 412-605-0131 or 412-605-0141

Participants interested in the CLAP Study may also be interested in:

 

The BREATHE Study

Follow the links below for more information.

Lab Website: https://hafemanresearchgroup.weebly.com

Lab Facebook: https://www.facebook.com/MoodDisorderEarlyInterventionResearch

 

SAND Study

 

Now recruiting participants. 

Principal Investigator: Anna Manelis, PhD
Co-Investigators: Mary Phillips, MD, Holly Swartz, MD

 

PUBLIC HEALTH RELEVANCE: The ability to prepare for emotional and cognitive tasks is critical to our daily life. Individuals with depression may experience impairment on tasks related to cognition and cognitive control. Macular degeneration also influences  This project aims to examine how age, symptoms of depression, and age-related macular degeneration (AMD) affect people’s ability to perform tasks requiring cognitive control.

 

Participation in the SAND Study may involve: One visit which will take 2-4.5 hours. Participation in the study will involve completing surveys and questionnaires as well as computer-based tasks. 

 

Participants must be:

  • Between the ages of 18 and 85
  • Have a history of depression OR have NO history of any psychiatric disorder
  • Have a diagnosis of Macular degeneration OR have NO diagnosis of macular degeneration

If eligible, participants will be compensated.

For more information:

Email: sand@upmc.edu (preferred)

Call: 412-605-0131   OR   412-605-0141